Tag: INR elevation

Trimethoprim-Sulfamethoxazole and Warfarin: How This Common Antibiotic Can Raise INR and Cause Bleeding 26 November 2025

Trimethoprim-Sulfamethoxazole and Warfarin: How This Common Antibiotic Can Raise INR and Cause Bleeding

Trimethoprim-sulfamethoxazole can sharply raise INR in patients on warfarin, increasing bleeding risk within days. Learn why this common antibiotic combo is dangerous, how to prevent it, and what alternatives exist.